Genital herpes is a cluster with small, fluid-filled sores, or lesions, that break. After the lesions (ulcers) break, painful upper thighs . are formed. Genital herpes is most commonly caused by the hsv simplex virus, HSV-2 but may also be caused by the actual HSV-1 virus. When an outbreak develops, it typically appears as one or more blisters on or around the reproductive organs or rectum. Genital herpes is a type of sexually transmitted infection (STI). It’s extremely common that you can catch it even if you’ve only had a few sexual partners. HSV-2 infection may also increase HIV-1 infectiousness by disrupting a genital mucosa and increasing the amounts of HIV in the genital tract3, allowing easier transmissibility of the virus. Moreover, the HIV viral weight in the blood of HIV-1 contaminated patients increases, at least temporarily, during episodes of HSV reactivation. HSV-2 is a lifelong disease and is found in nearly 80% regarding HIV-infected patients. Once acquired, herpes cycles between latency (hidden inside nerves), asymptomatic genital excretion of the virus (‘shedding’), and clinical reactivations which could produce painful ulcers near the genitalia.